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Fermeast™ SP

Fermeast™ SP is a dried sake yeast containing 0.2 wt% or more of spermidine(SPD). It is also rich in yeast-derived nutritional components (vitamins, amino acids, minerals, etc.).


SPD is a Key to Antiaging.

Spermidine(SPD) is a type of polyamine. Polyamines are present in almost all living organisms, from microorganisms to plants and higher animals, and are components that play an important role in cell proliferation in living organisms. Putrescine, spermidine(SPD), and spermine are known as typical polyamines in the human body.
The concentration of SPD in the body decreases with aging (Fig. 1), but it can be supplemented by diet. SPD is abundant in traditional Japanese foods such as fermented foods and is an ingredient with abundant eating experience. Fermeast™ SP assists in dietary intake of SPD.

Fig. 1 Concentration of SPD in human blood
Spermidine (SPD)

Chemical formula :C7H19N3


Examination item Value of standard Test method
Property yellowish-brown powder, an alien substance not recognized Visual inspection
SPD content > 0.2% HPLC
Water < 6% Loss on drying test
Arsenic < 2ppm(as As2O3 Atomic absorption method
Heavy metal < 20ppm(as Pb) Sodium sulfide colorimetric method
General bacteria < 1,000CFU/g Examination of food hygiene guidance (JP)
Coliform bacteria Negative
Fungus < 100CFU/g


Analysis level (in 100g)
Energy 328Kcal
Protein 37.5g
Lipid 10.5g
Carbohydrate 40.4g
Ash 7.5g
Water 4.1g
Sodium 0.02g

*This is an analysis level of the arbitrary lot and is not value of standard.


Size Inner bag Outer package
10kg(5kg×2bags) plastic bag corrugated cardboard case
1kg aluminum bag corrugated cardboard case


Safety Data

text Acute toxicity test Mutagenicity test 90 days repeat-dose study 28-day repeated over -oral administration Human test (1.5g/day)
result LD50 > 5,000mg/kg Negative ADI > 1,000mg/kg/day No adverse events

Storage method

Seal and avoid moisture absorption, store at room temperature and in the dark

Expiration date

2 years from the date of manufacture

Inquiries Concerning Products

Basic Chemicals Business Sector
Life Sciences Division
TEL:+81-3-3283-4893 / FAX:+81-3-3214-0930